Bioinformatics

Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data?_x005F_x000D_ Algorithm..

When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in..

Based on our knowledge of the functioning human brain, ANNs (artificial neural networks) serve as a modern paradigm for computing. Drawing on the author’s substantial experience, this book provides a comprehensive introduction and practical guide to the development, optimization, and application of ..

The 9th International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2015) was held on September 18-20, 2015, Shanghai, China. This proceedings volume assembles papers from various professionals engaged in the fields of Biomedical Engineering, Bioinformatics and Computational Biology..

Written by SeqAn project founders, this book describes the general library design of SeqAn. It introduces biological sequence analysis problems, discusses the benefit of using software libraries, summarizes SeqAn design principles and goals, details SeqAn programming techniques, and demonstrates the..

Emphasizing the search for patterns within and between biological sequences, trees, and graphs, this book shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis of genomic, transcriptomic, proteomic, metabolomic, and interactomic data...

Written by a dynamic team of highly regarded researchers, many of whom pioneered current methodologies in computer-assisted research in the life sciences, this interdisciplinary handbook covers terminology, software, and applications of computational biology. It provides clearly written yet authorit..

This textbook presents modern algebra from the ground up using numbers and symmetry. The idea of a ring and of a field are introduced in the context of concrete number systems. Groups arise from considering transformations of simple geometric objects. The analysis of symmetry provides the student wi..

Integrating the studies of epilepsy, neurosciences, computational neurosciences, mathematics, physics, engineering, and medicine, this volume provides the first means to a clear, structured, and enriching multidisciplinary perspective for developing students, researchers, and clinicians in the field..

Integrating the studies of epilepsy, neurosciences, computational neurosciences, mathematics, physics, engineering, and medicine, this volume provides the first means to a clear, structured, and enriching multidisciplinary perspective for developing students, researchers, and clinicians in the field..

This book is a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have now adopted the use of digital images. The text discusses basic imaging informatics proto..

Extensively classroom-tested in undergraduate and graduate courses, this self-contained book presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological ..