Oral Drug Absorption

Now in its second edition, this volume thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The book reviews major advances in pharmacokinetic modeling and profiling. It discusses methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR and IR formulations. This edition adds information about bioequivalence studies, biowaiving, formulation screening, and different approaches from U.S. industry and European industry perspectives. Case-based examples and a supplementary interactive CD-ROM are included.