Radiotherapy Treatment Planning

This volume describes tumor cell inactivation from a radiation physics perspective and offers appropriate linear-quadratic parameters for modeling tumor and normal tissue responses. It describes cell killing by radiation from two independent mechanisms: alpha and beta. The authors emphasize the biophysical factors associated with radiation cell killing and provide numbers that can be input into TCP and NTCP models. They also explain how the physical factors of fraction size, dose rate, and radiation quality are used in radiotherapy.