Diffuse Optical Tomography

Diffuse optical tomography (DOT) is an imaging method based on near infrared optical technologies and model-based inverse computations. It can provide spatial distributions of intrinsic tissue optical properties or molecular contrast agents through model-based reconstruction algorithms using NIR measurements along or near the boundary of tissue. This book covers almost every aspect of DOT—from mathematics, reconstruction algorithms, instrumentation, and phantom experiments to clinical applications. The text covers the fundamental principles, including its mathematical foundations and computational methods, and explains how to set up experimental image systems and how to adapt laboratory study results for use in clinical applications.