Structural Genomics on Membrane Proteins

This book presents various structural genomics approaches and explores novel technologies that will potentially accelerate breakthroughs in drug discovery. More than 40 top researchers write about their recent progress and challenges they face. They provide an excellent overview on novel research in bioinformatics, modeling on membranes, and the latest technological developments being employed in expression, purification, and crystallography to obtain high-resolution structures on membrane proteins. The book includes examples of studies on whole genomes of specific organisms and gene protein families and sections on signaling, solubilization, and recombinant expression technologies.